اطلاعات تماس با دکتر جمشید دونلو متخصص مغز و اعصاب نشاني ۱:تهران - ميدان فاطمي ( جهاد ) بيمارستان سجاد(صبح روزهای فرد)- تلفن ۶-۸۸۹۵۷۳۹۱ نشاني ٢ : تهران - بزرگراه جلال آل احمد- مقابل دانشگاه تربيت مدرس - كلينيك باران(عصرها 3تا6) - تلفن ۸۸۳۳۴۹۷۵
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The timeframe during which recovery and recurrence occur in people with a first episode of mania are somewhat variable. A meta-analysis by Andréanne Gignac and colleagues published in the Journal of Clinical Psychiatry in 2015 offers some new information. The meta-analysis included eight studies with a total of 734 participants in a first episode of mania. Syndromal recovery rates (when patients no longer met diagnostic criteria for bipolar disorder) were 77.4% at six months after first episode of mania and 84.2% at one year after. However, some symptoms lingered, and only 62.1% of patients reached a period of symptomatic recovery within one year.
Recurrence rates were 25.7% within six months, 41.0% within one year, and 59.7% by four years. Those who were younger at the time of the first episode were at higher risk for relapse within one year.
GLASGOW, Scotland — New data from a large international registry of thrombolysis in stroke suggest that tissue plasminogen activator (tPA, alteplase) is safe to use in patients with very severe strokes.
"We did not find any excess bleeding risk in the population with very severe stroke," defined as a National Institutes of Health Stroke Scale (NIHSS) score of greater than 25. Lead author Michael Mazya, MD, Karolinska Institutet, Stockholm, Sweden, concluded. He presented the data here at recent inaugural European Stroke Organisation (ESO) Conference 2015.
"Our opinion is that an NIHSS score of over 25 should not be a contraindication for tPA," he added. "These patients should be treated rapidly and no differently from patients with strokes of lesser severity."
Co-chair of the session at which the study was presented, Robert Mikulik, MD, Masaryk University Brno, Czech Republic, commented to Medscape Medical News: "tPA looked safe in very severe strokes in this study. Putting this together with what we already know, it appears that tPA is safe regardless of NIHSS score."
European Stroke Organisation (ESO) Conference 2015. Abstract 228. Presented April 18, 2015.